Hyrogel pro
Soap and water have been the cornerstone of hygiene and cleanliness for centuries. While they are effective for many purposes, Noviryn has expanded its advanced technology in newly developed hygienic hand cleansers to address limitations, meet the needs of modern lifestyles, and respond to emerging health challenges.
The COVID-19 pandemic highlighted the need for robust hygiene practices. Noviryn's advanced solutions can break down complex substances that traditional methods alone cannot effectively remove, helping to reduce the spread of pathogens, support public health initiatives, and reduce the burden on healthcare systems. Noviryn's enhanced effectiveness in response to emerging health challenges upgrades the fundamental focus of just soap and water. Embracing technological advancements in hygiene enhances individual well-being and contributes to the broader public health sustainability goals.
THE ROLE OF BIOFILMS
The recent pandemic has shown that bacteria and viruses struggle to survive in a planktonic (free-living/stand-alone) state due to several environmental challenges and biological limitations. As a result, bacteria and viruses seek survival through attachment to non-living fluids such as sweat, saliva, mucus, and extracellular matrix known as biofilm. Bacteria and viruses are protected by the polymer matrix that shields them from environmental stressors and antimicrobial agents in biofilms. Planktonic bacteria lack this protective barrier, making them more vulnerable.
Viruses are obligate intracellular parasites that require a host cell to replicate. Viruses are outside host cells and cannot reproduce in a planktonic state. They must rely on transmission vectors to remain viable and initiate infection and propagation. Biofilms and bodily fluids can serve as reservoirs for viral transmission and represent a unique challenge for infection control.
Pathogenic bacteria and viruses find survival outside a host organism challenging due to the immune system's mechanisms for identifying and eliminating these invaders. Planktonic pathogens are more easily recognized and attacked by host immune cells than those in biofilms or within host cells. Biofilms protect microorganisms by enabling survival by defending against environmental stressors and antibiotics. Negatively charged groups play a crucial role in biofilms' structural ' integrity and function. The negative charge can help stabilize the biofilm by binding cations from the environment, and it also influences interactions with surfaces and antimicrobial agents.
THE SOLUTION
Noviryn's formulation effectively cleans negatively charged matter such as mucus, saliva, or polymeric matrices. Cationic surfactants have a positively charged hydrophilic head and a hydrophobic tail.
The cleaning mechanism involves several steps:
1. **Penetration and Disruption**: The hydrophobic tails of the surfactants penetrate the polymer matrix, disrupting the cohesive forces within the polymer. This can help break down the polymer structure, making removing it easier.
2. ** Wetting**: The cationic surfactant molecules adsorb onto the polymer's surface, reducing the surface tension and increasing wettability.
3. **Emulsification and Solubilization**: The surfactant molecules can emulsify and solubilize the polymer fragments, dispersing them into the cleaning solution.
4. **Electrostatic Interactions**: The positively charged head groups of the cationic surfactants can interact with negatively charged sites on the polymer or other matter/fluids, detaining the polymer from the surface.
5. **Absorption**: Catalytic surfactants absorb negatively charged proteins such as saliva, sweat, or mucus through electrostatic attraction. This property is superior to soap, as it enhances cleansing and removal.
Cationic surfactants are particularly effective against negatively charged functional groups, such as carboxylates or sulfonates. These electrostatic interactions can enhance the cleaning efficiency by weakening the adhesion. Cationic surfactants effectively clean polymers off surfaces, particularly when the polymer or surface has negatively charged components.